Adenylate kinase locus 1 genetic polymorphism and type 2 diabetes

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Adenylate kinase locus 1 genetic polymorphism and type 2 diabetes

AK1 catalyzes the reversible reaction ATP+AMP  2ADP thus contributing to the regulation of relative concentration of these important nucleotides. Intracellular ATP is a storage of energy for cellular processes, moreover extracellular ATP together with ADP, AMP and adenosine are critical signalling molecule for sending messages to nearby cells acting on P1 and P2 receptors. AK1 shows a genetic ...

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a study of adenylate kinase locus 1 (ak1) genetic polymorphism in diabetic pregnancy

background: previous studies suggest that adenylate kinase locus 1 (ak1) has an important role in the control of blood glucose level and in the glycation of structural and functional proteins in type 2 diabetes and in the balanced development of feto-placental unit in healthy puerperae (hp). in this study, an attempt was made to investigate the relationship of ak1 with maternal and neonatal par...

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A Study of Adenylate Kinase Locus 1 (Ak1) Genetic Polymorphism in Diabetic Pregnancy

BACKGROUND Previous studies suggest that adenylate kinase locus 1 (Ak 1 ) has an important role in the control of blood glucose level and in the glycation of structural and functional proteins in type 2 diabetes and in the balanced development of feto-placental unit in healthy puerperae (HP). In this study, an attempt was made to investigate the relationship of Ak 1 with maternal and neonatal p...

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Short Communication A Study of Adenylate Kinase Locus 1 (Ak1) Genetic Polymorphism in Diabetic Pregnancy

Background: Previous studies suggest that adenylate kinase locus 1 (Ak1) has an important role in the control of blood glucose level and in the glycation of structural and functional proteins in type 2 diabetes and in the balanced development of fetoplacental unit in healthy puerperae (HP). In this study, an attempt was made to investigate the relationship of Ak1 with maternal and neonatal para...

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Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes.

OBJECTIVE Latent autoimmune diabetes in adults (LADA) is often considered a slowly progressing subtype of type 1 diabetes, although the clinical picture more resembles type 2 diabetes. One way to improve classification is to study whether LADA shares genetic features with type 1 and/or type 2 diabetes. RESEARCH DESIGN AND METHODS To accomplish this, we studied whether LADA shares variation in...

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ژورنال

عنوان ژورنال: Health

سال: 2011

ISSN: 1949-4998,1949-5005

DOI: 10.4236/health.2011.32014